Its interesting, but from an economic/resource/infrastructure perspective i see the following:
High-sec -> industrialized civilization, few resources, plenty of facilities to work it, high taxes
Low-sec -> civilization borders, pockets of industralized/advanced infrastructure, pockets of valuable resources, low-taxes
Null-sec -> the frontier, resources all around, little civilization, little industrialization, no-taxes (or very low if only applied to sov owners)
So in a way,
High-sec for large scale manufacturing, but you pay the price, its throughput vs taxes (time vs cost)
High-sec for highly advanced research (t3 reserve engineering)
Acquiring resources is difficult as quantities are not enough, and some are not even present.
Low-sec allows for the same as high-sec at lower costs, but only in certain spots....(conflict driver)
Acquiring resources is possible, but the spread through small pockets
Null-sec requires deployment of infrastructure (investment vs time)
Null-sec has all the resources
Null-sec has no taxes
So in essence i wouldnt want special cases for Arrays specific to low-sec or null-sec, i would prefer that as long as players "invested" in a location, then it would become valuable.
POS with arrays in low-sec would be nice, specially if you were aligned with the faction owning said space (bonuses for being in FW)......
And a clear progression from worst to best between : ( high-sec station -> outpost -> POS -> upgraded outpost )
So a caldari outpost with all the science upgrades would be overpowered in terms of churning copies and researched BPOs/invention runs......making null worthy but as long as you went all the way into the expenditures.