Problems that arise from various tubetry in various orificery.
Also pod goo related problems if all the orifices are not plugged.
There is nothing like crapping out a gallon of pod goo because you wanted to fly au naturel, also the infections that it brings.
I recently won a sub to EON. I've been enjoying the Knowledgebase articles EON carries, while also (sweetly, gently) raging that this info isn't available to the general audience.
There's an article in the spring 2011 EON about hydrostatic fluid (pod goo). I've quoted a few paragraphs from it before, so let me cut and paste:
As a matter of course, hydrostatic fluid is loaded with various kinds of nanotech, from bio-engineered organisms to more complex nanomachines that work to cleanse the fluid of impurities akin to an elaborate extra-corporeal immune system. Such a mix of nanites can be very complex, almost like an entire ecosystem designed to eliminate poisons and bacteria from the fluid in which the pilot is immersed, as well as material from the body that might be collected later by unscrupulous elements looking to utilize material that contains capsuleer DNA.
I've always assumed the default is that you don't wear clothes in the pod, by the way: I
think there was even a comment at its launch that the black shorts on the pilot in the
Incarna depodding teaser were there because of ratings. I'm aware that there's also a tradition of pod suits, but my reading of the current work on pod goo is that you'd be far better off without a suit.
(Also, what's amiss with this hypothetical pilot's sphincters? "Gallons"? Please keep such pilots away from baths, pools and jacuzzis.)